Homeless youth living on the streets of large cities and engaging in unprotected sex are at risk of infections with C. trachomatis [CT], N. gonorrhoeae [GC], T. vaginalis [TV], and human papillomavirus [HPV]. The APTIMA transcription mediated amplification [TMA] assays are sensitive and specific for detecting genital infections using various sample types.
Using APTIMA assays to screen genital infections in this younger, largely asymptomatic population demonstrated a high burden of infection. The use of multiple assays enabled confirmation of results and early treatment. Infections with several organisms and HPV genotypes indicate a public health concern for the sexual health of these homeless individuals.